Validation of Next Generation Sequencing Cancer Panels for Clinical Somatic Mutation Profiling-- Identification of Source of Variations and Artifacts using FFPE Tissues

Ken CN Chang*, Yun Zhao, John Kang, Saumya Pant, Ping Qiu, Bo Wei, Russell Weiner and Matthew J Marton

Use of a Next Generation Sequencing (NGS)-based test as a clinical trial assay requires that the test be analytically validated to CLIA/CAP regulations. During the course of ana..Посмотреть больше»

Genes Associated with Increased Fasting Glucose in Patients with Schizophrenia Spectrum Disorders

Dzana Sudic Hukic, Eric Olsson, Agneta Hilding, Claes-Goran Ostenson, Harvest F Gu, Ewa Ehrenborg, David Erlinge, Gunnar Edman, Martin Schalling, Catharina Lavebratt and Urban Osby

Background: Metabolic risk factors represent a major cause of increased coronary heart disease morbidity and mortality among psychosis patients. Although antips..Посмотреть больше»

Novel Nicotinic Receptor Agonist Reduces Hyperalgesia and Allodynia of Neuropathic Pain in Diabetic Rats

Roberto C Debom, Margarete M Trachez, Gisele Zapata Sudo, Jaqueline S da Silva, Kesley M Oliveira, Ariel L Garcia, Lidiane M Godoy, Ogari C Pacheco and Roberto T Sudo

Diabetic Peripheral Neuropathic Pain (DPNP) has been attributed to abnormal glucose metabolism and oxidative stress. It is among the most common consequence of chronic diabetes ..Посмотреть больше»

Identifying Climate Change Signals from Downscaled Temperature Data in Umuahia Metropolis, Abia State, Nigeria

Ozabor F and Nwagbara MO

This study was about Identifying climate change, by adopting the downscaling techniques in Umuahia metropolis. The study adopted ex-post-facto research design and data for maxim..Посмотреть больше»

Exocrine Pancreatic Insufficiency, as Assessed by Fecal Elastase-1 Levels, in Diabetic Patients: An Estimate of Prevalence in Prospective Studies

Angelo Andriulli, Antonio Massimo Ippolito, Virginia Festa, Maria Rosa Valvano, Antonio Merla, Fabrizio Bossa, Grazia Niro, Grazia Napolitano, Luigi Benini and Italo Vantini

Objective: To assess the prevalence of pancreatic exocrine insufficiency (PEI) inpatients with diabetes mellitus (DM).

Design: Meta-a..Посмотреть больше»

Proximate Analysis and Mineral composition of Some Selected Medicinal plants of Malakand Division, Pakistan

Sana Ullah*, Mati Ullah, Gul Rahim, Saad Khan1 and Izhar Ullah

The sole objective was to screen five plants for proximate constituents and mineral analysis. These plants include Perilla frutescence, Zanthoxylum armatum, Justicia adhatoda, M..Посмотреть больше»