QSAR Model for Androgen Receptor Antagonism - Data from CHO Cell Reporter Gene Assays

Gunde Egeskov Jensen, Nikolai Georgiev Nikolov, Karin Dreisig, Anne Marie Vinggaard and Jay Russel Niemela

For the development of QSAR models for Androgen Receptor (AR) antagonism, a training set based on reporter gene data from Chinese hamster ovary (CHO) cells was constructed. The tra..Посмотреть больше»

Multiple Drug Induced Hypersensitivity Syndrome Reactions in a Patient with Drugs that Have Known HLA Associations for Reactions

Khan S, Bhartia S and Roy S

We report a rare case of a patient with chronic myeloid leukaemia (CML) who had severe drug hypersensitivity reactions with not only allopurinol and imatinib therapies for the C..Посмотреть больше»

Central Retinal Artery Occlusion Following Central Retinal Vein Occlusion- A Case Report

Umi Kalthum Md Noh, Sin Yee Fang and Norshamsiah Md Din

A 73-year-old gentleman with diabetes mellitus was found to have impending central retinal vein occlusion (CRVO), on routine eye check-up. Despite initiation of..Посмотреть больше»

Astragaloside IV and Statin Increased the Islet Function and Proliferation for Beta Cells in STZ-Induced Diabetic Mice

Mincai Li, Tonghui She, Yapin Gan, Juan Shao, Suqin Li, Wenli Liao, Hongli Xia, Liangzu Yu and Zhengwu Hu

Objective: Diabetic

hyperglycemia

causes a variety of pathological process involved in metabolic changes. Astragaloside IV (AS-IV) was widely used for the tr..Посмотреть больше»

Withania somnifera- Characteristics, Uses and Side effects

Robert W Buchanan*

Withania somnifera is an annual evergreen shrub belonging to family Solanaceae grows in India, the Middle East, and parts of Africa. Though it is used for medicinal pur..Посмотреть больше»

Molecular Docking Analysis and Evaluation for Antibacterial Activity of Chemical Constituents From the Stem Barks of Podocarpus falcatus

Desalegn Abebe Deresa*, Zelalem Abdissa, Getahun Tadesse Gurmessa and Negera Abdissa

Chromatographic separation of an equal ratio of CH2Cl2-MeOH extract of the stem barks of Podocarpus falcatus led to the isolation of three compounds 1-3. The structures of the c..Посмотреть больше»