Sangun Lee, Junichi Hashimoto, Takao Suzuki, Atsuko Satoh, Barry Kavanagh, Kiyonori Yamai and Shinji Ohta
Aims: In this study, we analyzed the effect of concentrated bovine-milk whey active protein (CBP) supplementcombined dynamic flamingo therapy (DFT) on bone metabolism and bone-related factors.
Methods: Subjects were menopausal women over 65 years of age, and they were divided into 3 groups C, DFT, and CBP-combined DFT (DFT-CBP) and analyzed for 2 months.
Results: The deoxypyridinoline (DPD) bone marker showed only a 27.7% decreased value in the DFT-CBP group after 2 months of treatment initiation, in comparison with the value before treatment (p<0.01). However, the calcitonin was found with significant changes in all groups, but the DFT and DFT-CBP groups demonstrated a similar pattern of changes. The DFT-CBP group showed a 30.1% increased value after 1 month of treatment initiation, in comparison with the value before treatment, and a 37.1% decreased value after 2 months of treatment initiation (p<0.001, in each).
Discussion: This study demonstrated the synergistic effect of CBP supplement and an exercise load such as DFT. On the basis of these results, with the presence of a synergistic effect of a lightly loaded exercise and supplementation, bone improvement in menopausal women can be expected.